The effect of migrastatics on cell migration examined in vitro using advanced non-invasive microscopy

Live cancer cells were exposed to the drugs with a presumed anti-migration activity. Effects on cell behavior and cell morphology were examined using a Quantitative Phase Microscope Q‑Phase which allowed non-invasive label-free monitoring of studied cell populations.

Obtained time-lapses of Quantitative Phase Images were used for the quantitative analysis of cell migration and cell morphology dynamics. Results confirm that QPI technology is a suitable tool for testing the drug’s effectiveness but also for the label-free identification of invasive cancer cell phenotypes. More details about the anti-metastatic potential assessment using Telight Q-Phase microscope can be found in the original poster below.