October 29, 2025
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Publications
A label-free method for measuring the composition of multicomponent biomolecular condensates
Composition of biomolecular condensates. Label-free measurements. Epirically validated in binary reconstituted mixtures, then used for analysis of concentrations of five macromolecular solutes in multicomponent condensates containing RNA and constructs of multiple RNA-binding proteins. Q-Phase was used as one of the key methods for analysis.
July 31, 2025
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Publications
Glucose-powered nanorobots mimic cellular communication
Glucose-powered nanorobots are capable of mimicking cellular communication. QPI technology has enabled accurate measurement of cell movement, proliferation, and dry mass.
June 24, 2025
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Publications
Mechanism of Biomolecular Condensate Disassembly in Cells
Discover how cells control biomolecular condensates, dynamic, droplet-like compartments without membranes using RNA-binding proteins. This study reveals the mechanisms behind their disassembly, offering fresh insights into cellular organization and development.
February 27, 2024
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Publications
Resources
Single-cell segmentation with two different QPI technologies
In esece, let us have a look how Q-Phase perfroms when it comes to cell imaging and segmentation, in comparison to Nanolives 3D Cell Explorer. Both have their advantages, let us have a closer look at what they are.
October 12, 2023
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Publications
Primary Assessment of Medicines with Quantitative Phase Imaging
A new PAMP framework helps to discover the potential of migrastatics. It utilizes the unique properties of QPI technology to do so.
May 12, 2023
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Publications
Single-shot super-resolution quantitative phase imaging allowed by coherence gate shaping
Improving the coherence gate in a holographic microscope leads to improved resolving power. This helps to achieve super-resolution for biological samples.
February 13, 2023
Publications
Pentamethinium salts suppress key metastatic processes
This comprehensive article covers many methods (including tests with 3D spheroids) and we are proud that Telight Q-Phase helped to prove the inhibitory effects on migration and cell growth driven by severe impact of salts on mitochondria functions.
February 12, 2023
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Publications
Magnetically Driven Microbots for Treatment of Prostate Cancer
A new and innovative research shows the possibility of magnetic microbots dissolving in cancer cells and inhibiting their growth.
June 10, 2022
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Publications
An efficient light collection by the cornea of the horseshoe crab
Trace of their ancestors can be dated from 485.4 million to 443.8 million years, which is why they are being referred to as living fossils sometimes...
June 9, 2022
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Publications
New publication in cancer research using QPI
The incidence of death caused by cancer has been increasing worldwide. The growth of cancer cells is not the main problem. The majority of deaths
May 5, 2022
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Publications
Cancer cell viscoelasticity measurement by quantitative phase and flow stress induction
A team of researchers introduced a novel, high-throughput method for measuring cell viscoelasticity using QPI and shear stress via fluid flow. Leveraging Q-Phase holographic microscope, this technique enables simultaneous assessment of cell mechanics, morphology, dry mass, and refractive index—advancing multimodal, label-free live-cell characterization.
July 13, 2021
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Publications
New publication in ACS Applied Materials & Interfaces
M. Fojtů, et al.: Silicane Derivative Increases Doxorubicin Efficacy in an Ovarian Carcinoma Mouse Model: Fighting Drug Resistance...
June 4, 2021
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Publications
Self-Supervised Pretraining for Transferable Quantitative Phase Image Cell Segmentation
Even though QPI data are suitable for cell instance segmentation there are still challenging cases to be solved (like populated areas of touching cells)...
June 4, 2021
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Publications
Oxidized polysaccharides for anticancer-drug delivery: What is the role of structure?
A new publication from Lukáš Münster and his team, released in April 2021 in the Carbohydrate Polymers journal...
January 12, 2021
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Publications
New article recognizing quantitative phase microscopy
A precise label-free method to measure the shape and composition of model condensates has been published by Brugués and Hyman labs from Max Planck Institute of Molecular Cell Biology and Genetics.
December 9, 2020
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Publications
New Article: Roadmap to holography
Journal of Optics has come with a wonderful overview of international activities in the field of holography - an exciting area of research leading to a wide range of innovations...
December 2, 2020
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Publications
New scientific articles published based on usage of multimodal microscope Q-Phase
Holographic microscope Q-Phase is used by scientists of Masaryk University to clarify various cell-related questions. Recently, they published...
August 18, 2020
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Publications
Quantitative phase imaging of spreading fibroblasts identifies the role of focal adhesion kinase in the stabilization of the cell rear
Scientists from the Czech Academy of Science, Institute of Microbiology, have currently published an article in Biomolecules journal, that exhibits...
February 2, 2020
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Publications
New article: A label-free assessment of cell death
For a label-free assessment of cell death without disrupting the routine culture, a new article released using Q-Phase as a robust instrument to detect and differentiate...
October 15, 2019
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Publications
Comparison of cell segmentation methods for label-free microscopy: Q-Phase between the best
An excellent comparison of the state-of-the-art cell segmentation methods for label-free microscopy has been lately done by scientists of Masaryk University...